For Research Purposes Only — Not for Human Consumption
KPV 10mg
Compound Overview & Research Information
KPV is a biologically active C-terminal tripeptide fragment (Lys-Pro-Val) of α-MSH. Lacking the melanocortin receptor binding responsible for pigmentation, KPV acts selectively through cellular peptide transporter PepT1 to inhibit the nuclear translocation of NF-κB. Widely studied in preclinical models of gut mucosal inflammation, inflammatory bowel disease, and dermatological wound healing. HPLC verified >99% purity. For laboratory research only.
Laboratory Specifications
ISO-Tested StandardFrequently Asked Research Questions
Does KPV cause melanogenesis or skin darkening like full-length α-MSH?+
No. KPV is a tripeptide fragment (Lys-Pro-Val) that completely lacks binding affinity for the melanocortin 1 receptor (MC1R) responsible for melanin synthesis, acting selectively on inflammatory signaling pathways.
What is KPV's primary mechanism of action in cellular assays?+
KPV enters target cells via the oligopeptide transporter PepT1 and directly inhibits the nuclear translocation of NF-κB, dramatically reducing pro-inflammatory cytokines such as IL-8, IL-6, and TNF-α.
What is the recommended storage procedure for KPV 10mg?+
Unopened lyophilized vials should be maintained at -20°C. Following reconstitution with sterile bacteriostatic water, refrigerate at 2°C–8°C.
How is purity verified on this product?+
Third-party laboratory analysis confirms >99.0% purity by analytical HPLC, with mass spectrometry confirming the 357.45 g/mol molecular weight.
How quickly are orders fulfilled?+
All orders placed by 2 PM EST ship the same business day from our US fulfillment center with end-to-end tracking.
Minimum 2 qty required ($150.00 total)
Accepted Payment Methods
This product is intended strictly for laboratory and in-vitro research. It has not been evaluated by the FDA and is not approved for human consumption, therapeutic use, or veterinary application. Always consult primary peer-reviewed literature and a qualified professional before drawing conclusions about any compound.
Everything You Need To Know About KPV 10mg
Recovery
